VANCOGENX® was the very first bone cement to be CE marked containing a combination of gentamicin and vancomycin. The synergistic behaviour of these two antibiotics makes this cement the best option [1] for challenging orthopaedic infections.
VANCOGENX uses special preparations and controlled processes to ensure an even distribution of fine antibiotics, resulting in bone cement with optimum strength and elution characteristics [2, 3].
References:
[1] Giavaresi G, Borsari V, Fini M, Giardino R, Sambri V, Gaibani P, Soffiatti R. Preliminary investigations on a new gentamicin and vancomycin-coated PMMA nail for the treatment of bone and intramedullary infections: An experimental study in the rabbit. J Orthop Res. 2008 Jun;26(6):785-92. doi: 10.1002/jor.20543.
[2] Bertazzoni Minelli E, Della Bora T, Benini A. Different microbial biofilm formation on polymethylmethacrylate (PMMA) bone cement loaded with gentamicin and vancomycin. Anaerobe. 2011 Dec;17(6):380-3. doi: 10.1016/j.anaerobe.2011.03.013. Epub 2011 Apr 16.
[3] Gallo J, Bogdanová K, Šiller M, Švábová M, Lošťák J, Kolář M. [Microbial and pharmacological characteristics of VancogenX]. Acta Chir Orthop Traumatol Cech. 2013;80(1):69-76. Czech.
VANCOGENX is a registered trademark of Tecres SpA
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